Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.56 |
| ▸ | FASN | P49327 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6383520 | 0.95 | FASN (0.51) | PPARGGPR132FASNMEN1KMT2A | |
| SCHEMBL7874876 | 0.94 | FFAR1 (0.52) | PPARGGPR132KMT2AFFAR1FFAR4 | |
| SCHEMBL27668986 | 0.94 | FFAR1 (0.52) | PPARGGPR132KMT2AFFAR1FFAR4 | |
| SCHEMBL8632033 | 0.94 | FFAR1 (0.52) | PPARGGPR132KMT2AFFAR1FFAR4 | |
| SCHEMBL8632039 | 0.94 | FFAR1 (0.52) | PPARGGPR132KMT2AFFAR1FFAR4 | |
| SCHEMBL7771650 | 0.93 | FASN (0.51) | PPARGGPR132FASNMEN1KMT2A | |
| Glycerin SCHEMBL4267527 | 0.88 | FFAR1 (0.51) | PPARGKMT2AFFAR1FFAR4FAAH | |
| SCHEMBL7148025 | 0.87 | GPR84 (0.53) | MEN1KMT2AFFAR1FFAR4 | |
| SCHEMBL9297272 | 0.87 | GPR84 (0.53) | MEN1KMT2AFFAR1FFAR4 | |
| SCHEMBL325989 | 0.87 | GPR84 (0.53) | MEN1KMT2AFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437694-B1 | Use of a hydroxyoctadécadiene acid, its keto-oxydized acid and their derivatives in the treatment of estrogen-dependent diseases, and pharmaceutical compositions thereof | Boots Pharma GmbH (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5102912-A | Antitumor, anticancer agents | KANOLDT ARZNEIMITTEL GMBH (DE) | 1992-04-07 | — | — | US | disclosed |
| EP-0437694-A1 | Use of a hydroxyoctadécadiene acid, its keto-oxydized acid and their derivatives in the treatment of estrogen-dependent diseases, and pharmaceutical compositions thereof | Boots Pharma GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |