SCHEMBL9505433

SCHEMBL9505433

CCNc1ccc(N)c(S(=O)(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTDSP1 Q9GZU7 1/20 0.59
EGFR P00533 1/20 0.42
LMNA P02545 3/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 3/20 0.41
HIF1A Q16665 1/20 0.41
RAPGEF4 Q8WZA2 1/20 0.41
MAPT P10636 4/20 0.40
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 4/20 0.40
GAA P10253 3/20 0.40
POLB P06746 3/20 0.40
RECQL P46063 3/20 0.40
CASP6 P55212 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ELAVL1 Q15717 1/20 0.40
ADRA2A P08913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8109155 0.87 CTDSP1 (0.46) CTDSP1EGFRLMNAHPGDHSD17B10
SCHEMBL15452139 0.83 CTDSP1 (0.59) CTDSP1EGFRLMNAHPGDHSD17B10
SCHEMBL9153705 0.82 CTDSP1 (0.51) CTDSP1EGFRRAPGEF4MAPTKDM4E
SCHEMBL9503206 0.81 CTDSP1 (0.56) CTDSP1EGFRHPGDHSD17B10HIF1A
SCHEMBL9156052 0.80 CTDSP1 (0.68) CTDSP1EGFRHIF1ARAPGEF4MAPT
Sulfuric Acid SCHEMBL7749074 0.80 ALDH1A1 (0.47) CTDSP1LMNAHPGDHSD17B10HIF1A
SCHEMBL9153963 0.80 CTDSP1 (0.49) CTDSP1EGFRRAPGEF4MAPTKDM4E
SCHEMBL8912707 0.80 CTDSP1 (0.56) CTDSP1HPGDMAPTKDM4EALDH1A1
SCHEMBL13214338 0.79 CTDSP1 (0.54) CTDSP1EGFRHPGDHSD17B10RAPGEF4
Sulfuric Acid SCHEMBL11044859 0.79 ALDH1A1 (0.46) CTDSP1LMNAHPGDHSD17B10HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0324373-B1 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AG (DE) 1993-12-08 EP disclosed
EP-0324372-B1 WATER SOLUBLE 2-NAPHTHOL AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
EP-0260806-B1 COLORATION PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-08 EP disclosed
US-5047515-A Monoazo Dyes HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
US-4881942-A HEATING, FIXING, CONTROLLING PH TO 5.8 TO 8.0 IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-21 US disclosed
EP-0324373-A2 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-19 EP disclosed
EP-0324372-A2 Water soluble 2-naphthol azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1989-07-19 EP disclosed
EP-0260806-A2 Coloration process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-23 EP disclosed
EP-0138303-A1 Naphthalene sulphonic acids IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-04-24 EP disclosed
EP-0090114-A2 Reactive dyes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-10-05 EP disclosed
EP-0066714-A2 Reactive dyestuffs BASF Aktiengesellschaft (DE) 1982-12-15 EP disclosed
US-4300902-A Coloration process IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-11-17 US disclosed
US-4191687-A Reactive dyestuffs containing the residue of 1-hydroxy-7-amino-8-(5'-amino-2',4'-disulphophenylazo)naphthalene-3,6-disulphonic acid IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-03-04 US disclosed