Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505459 | 0.89 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9504601 | 0.81 | CYSLTR2 (0.41) | CYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9504617 | 0.78 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL10482240 | 0.75 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| Pobilukast SCHEMBL29473536 | 0.74 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL6437479 | 0.74 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9560172 | 0.74 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| Pobilukast SCHEMBL125952 | 0.74 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9534035 | 0.74 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL9534048 | 0.74 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |