SCHEMBL9505513

SCHEMBL9505513

CCCCCC1CCC(O)(c2cc(F)c(F)c(F)c2)CC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.36
OPRK1 P41145 2/20 0.36
OPRL1 P41146 2/20 0.36
CCR1 P32246 1/20 0.34
CYP1A2 P05177 2/20 0.33
NAMPT P43490 1/20 0.31
CYP3A4 P08684 2/20 0.31
CYP2C8 P10632 2/20 0.31
S1PR3 Q99500 2/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
OPRD1 P41143 1/20 0.30
CNR1 P21554 2/20 0.30
CNR2 P34972 2/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013287 0.89 CYP1A2 (0.32) OPRM1OPRK1OPRL1CYP1A2CNR1
SCHEMBL7859980 0.87 OPRM1 (0.36) OPRM1OPRK1OPRL1CYP1A2NAMPT
SCHEMBL10798909 0.86 OPRM1 (0.39) OPRM1OPRK1OPRL1CYP1A2OPRD1
SCHEMBL29097689 0.83 ESR2 (0.35) OPRM1OPRK1OPRL1CYP1A2OPRD1
SCHEMBL9763553 0.81 MEN1 (0.39) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL9764010 0.80 MEN1 (0.38) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL9763536 0.80 MEN1 (0.38) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL9763541 0.80 MEN1 (0.38) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL9763963 0.80 MEN1 (0.38) CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL9763952 0.80 MEN1 (0.38) CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0387032-B1 TRIFLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME CHISSO CORP (JP) 1993-06-16 EP disclosed
US-5032313-A Trifluorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1991-07-16 US disclosed
EP-0387032-A1 Trifluorobenzene derivatives and liquid crystal compositions containing the same Chisso Corporation (JP) 1990-09-12 EP disclosed