Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA7 | P43166 | 6/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | APOB | P04114 | 1/20 | 0.39 |
| ▸ | MTTP | P55157 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4853275 | 0.85 | MCHR1 (0.59) | CA1CA2CA12CA7CA14 | |
| SCHEMBL10405996 | 0.83 | MCHR1 (0.54) | CA1CA2CA12CA7CA14 | |
| SCHEMBL10405252 | 0.83 | CA1 (0.61) | CA1CA2CA12CA7CA14 | |
| SCHEMBL5737230 | 0.82 | CA1 (0.42) | CA1CA2CA12CA7CA14 | |
| SCHEMBL7275227 | 0.82 | CA1 (0.60) | CA1CA2CA12CA7CA14 | |
| SCHEMBL10405777 | 0.79 | CA1 (0.53) | CA1CA2CA12CA7CA14 | |
| SCHEMBL6400837 | 0.78 | ALDH1A1 (0.40) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11444221 | 0.77 | CA1 (0.61) | CA1CA2CA12CA7CA14 | |
| SCHEMBL5738672 | 0.77 | CA1 (0.55) | CA1CA2CA12CA7CA14 | |
| SCHEMBL5738892 | 0.77 | CA1 (0.55) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330380-B1 | NOVEL INDANOXYACETIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1993-06-23 | — | — | EP | disclosed |
| US-4975460-A | INHIBITION OF PLATELET AGGREGATION | TANABE SEIYAKU CO., LTD. (JP) | 1990-12-04 | — | — | US | disclosed |
| EP-0330380-A2 | Novel indanoxyacetic acid derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |