Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.50 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672906 | 0.91 | TSHR (0.59) | TSHRSLC22A16HPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL434986 | 0.90 | TSHR (0.57) | TSHRSLC22A16HPGDALDH1A1TP53 | |
| Iodide SCHEMBL1255401 | 0.90 | TSHR (0.57) | TSHRSLC22A16HPGDALDH1A1TP53 | |
| Fluoride Ion SCHEMBL1252819 | 0.90 | TSHR (0.57) | TSHRSLC22A16HPGDALDH1A1TP53 | |
| Bromide SCHEMBL1254203 | 0.90 | TSHR (0.57) | TSHRSLC22A16HPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL28204650 | 0.88 | TSHR (0.55) | TSHRSLC22A16HPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL28204649 | 0.86 | TSHR (0.53) | TSHRSLC22A16HPGDALDH1A1TP53 | |
| SCHEMBL95157 | 0.78 | TSHR (0.64) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9503575 | 0.76 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL29254308 | 0.76 | TSHR (0.47) | TSHRSLC22A16HPGDALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187281-B1 | NOVEL CARBOXYLATE POLYMERS AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4808668-A | SEWAGE TREATMENT FLOCCULANT | ALLIED-SIGNAL INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0187281-A2 | Novel carboxylate polymers and processes for their preparation and use | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1986-07-16 | — | — | EP | disclosed |