Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503879 | 0.92 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL9507452 | 0.91 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9505637 | 0.76 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL6931227 | 0.73 | MAPT (0.32) | SMN1; SMN2 | |
| SCHEMBL27336395 | 0.72 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL41918 | 0.71 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL15155490 | 0.70 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28592182 | 0.70 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11360471 | 0.70 | TSHR (0.44) | TSHRHPGDALDH1A1TP53HIF1A | |
| Iodide SCHEMBL27806997 | 0.70 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187281-B1 | NOVEL CARBOXYLATE POLYMERS AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1993-06-23 | — | — | EP | claimed |
| US-4808668-A | SEWAGE TREATMENT FLOCCULANT | ALLIED-SIGNAL INC. (US) | 1989-02-28 | — | — | US | claimed |
| EP-0187281-A2 | Novel carboxylate polymers and processes for their preparation and use | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1986-07-16 | — | — | EP | claimed |
| EP-0187281-B1 | NOVEL CARBOXYLATE POLYMERS AND PROCESSES FOR THEIR PREPARATION AND USE | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4808668-A | SEWAGE TREATMENT FLOCCULANT | ALLIED-SIGNAL INC. (US) | 1989-02-28 | — | — | US | disclosed |
| EP-0187281-A2 | Novel carboxylate polymers and processes for their preparation and use | RHONE-POULENC SPECIALTY CHEMICALS CO. (US) | 1986-07-16 | — | — | EP | disclosed |