SCHEMBL9505671

SCHEMBL9505671

CCCC/C=C(\C(=O)O)S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.47
GRIK1 P39086 1/20 0.42
F7 P08709 2/20 0.37
F3 P13726 2/20 0.37
TSHR P16473 1/20 0.34
PPARA Q07869 3/20 0.33
TERT O14746 3/20 0.33
MAPT P10636 2/20 0.33
BLM P54132 2/20 0.33
HSD17B10 Q99714 2/20 0.33
FABP4 P15090 2/20 0.33
PTPN1 P18031 2/20 0.33
PPARG P37231 2/20 0.33
PPARD Q03181 2/20 0.33
GMNN O75496 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10600654 1.00 EP300 (0.47) EP300GRIK1F7F3TSHR
SCHEMBL27660066 0.92 EP300 (0.58) EP300F7F3PPARATERT
SCHEMBL22983 0.88 GRIK1 (0.39) EP300GRIK1CYP1A2CYP2C19
SCHEMBL7068402 0.88 GRIK1 (0.39) EP300GRIK1CYP1A2CYP2C19
SCHEMBL8089344 0.82 GRIK1 (0.38) EP300GRIK1F7F3TSHR
SCHEMBL7529207 0.81 GRIK1 (0.37) EP300GRIK1F7F3TSHR
SCHEMBL11970131 0.79 GRIK1 (0.35) EP300GRIK1
SCHEMBL165515 0.79 GRIK1 (0.35) EP300GRIK1
SCHEMBL27679374 0.79 GRIK1 (0.35) EP300GRIK1
SCHEMBL11008690 0.78 CNR1 (0.34) CYP1A2CYP2C19FAAHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0290936-B1 LIQUID ELECTROSTATIC DEVELOPERS COMPOSED OF BLENDED RESINS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-11 EP disclosed
EP-0290936-A1 Liquid electrostatic developers composed of blended resins E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-11-17 EP disclosed
US-4772528-A NEGATIVELY CHARGED RESIN PARTICLES, IMAGING, RESOLUTION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-09-20 US disclosed
EP-0251215-A2 Chargeable resins for liquid electrostatic developers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-07 EP disclosed
US-4681831-A NONPOLAR LIQUID, ANIONIC POLYMERS, IONIC OR ZWITTERIONIC CHARGE DIRECTOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-07-21 US disclosed