Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505535 | 0.94 | ACAT1 (0.69) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9502175 | 0.93 | ACAT1 (0.70) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9506109 | 0.93 | ACAT1 (0.53) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9502436 | 0.91 | ACAT1 (0.61) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9503973 | 0.90 | ACAT1 (0.60) | ACAT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL9502303 | 0.89 | ACAT1 (0.61) | ACAT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL9502289 | 0.88 | ACAT1 (0.59) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9506099 | 0.88 | GAA (0.51) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9502971 | 0.86 | ACAT1 (0.59) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 | |
| SCHEMBL9502156 | 0.86 | ACAT1 (0.59) | ACAT1SMN1; SMN2ALDH1A1NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |