Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502933 | 0.91 | ACAT1 (0.82) | ACAT1SMN1; SMN2MAPK1HTTCA1 | |
| SCHEMBL9366207 | 0.90 | ACAT1 (0.83) | ACAT1SMN1; SMN2MAPK1HTTNR1H4 | |
| SCHEMBL9366147 | 0.90 | ACAT1 (0.83) | ACAT1SMN1; SMN2MAPK1HTTNR1H4 | |
| SCHEMBL9361223 | 0.90 | ACAT1 (0.83) | ACAT1SMN1; SMN2MAPK1HTTNR1H4 | |
| SCHEMBL9502491 | 0.86 | ACAT1 (0.62) | ACAT1SMN1; SMN2MAPK1HTTCA1 | |
| SCHEMBL9502984 | 0.86 | ACAT1 (0.62) | ACAT1SMN1; SMN2MAPK1HTTCA1 | |
| SCHEMBL9502255 | 0.85 | ACAT1 (0.72) | ACAT1SMN1; SMN2MAPK1HTTCA1 | |
| SCHEMBL9502212 | 0.85 | ACAT1 (0.72) | ACAT1SMN1; SMN2MAPK1HTTCA1 | |
| SCHEMBL9502100 | 0.85 | ACAT1 (0.72) | ACAT1SMN1; SMN2MAPK1HTTCA1 | |
| SCHEMBL9503848 | 0.85 | ACAT1 (0.60) | ACAT1SMN1; SMN2MAPK1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543891-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003413-A1 | DIPHENYLUREA DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |