SCHEMBL95057

SCHEMBL95057

Cc1nc(C)c(CO)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263398 0.81 ALDH1A1 (0.45)
SCHEMBL27748701 0.80
Iodide SCHEMBL28449438 0.79 ALDH1A1 (0.44)
SCHEMBL15437081 0.78 HSD17B10 (0.36)
SCHEMBL2244526 0.78
SCHEMBL18256087 0.78 ALDH1A1 (0.43)
SCHEMBL755570 0.77
SCHEMBL13458766 0.76
SCHEMBL4295925 0.76
SCHEMBL1846903 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346564-A1 INHIBITORS OF PARG ARASE THERAPEUTICS INC (US) 2025-11-13 US disclosed
US-12227484-B2 Inhibitors of PARG ARASE THERAPEUTICS INC. (US) 2025-02-18 US disclosed
EP-4479387-A1 INHIBITORS OF PARG ARase Therapeutics Inc. (US) 2024-12-25 EP disclosed
CN-119013261-A Inhibitors of PARG 雅瑞斯医疗公司 2024-11-22 CN disclosed
WO-2023175184-A1 2,4-DIOXO-1,4-DIHYDROQUINAZOLINE DERIVATIVES AS PARG INHIBITORS FOR THE TREATMENT OF CANCER FORX THERAPEUTICS AG (CH) 2023-09-21 WO disclosed
WO-2023175184-A1 2,4-DIOXO-1,4-DIHYDROQUINAZOLINE DERIVATIVES AS PARG INHIBITORS FOR THE TREATMENT OF CANCER FORX THERAPEUTICS AG (CH) 2023-09-21 WO disclosed
US-20230265057-A1 INHIBITORS OF PARG ARASE THERAPEUTICS INC. 2023-08-24 US disclosed
WO-2023154913-A1 INHIBITORS OF PARG ARASE THERAPEUTICS INC. (US) 2023-08-17 WO disclosed
CN-111225915-B Imidazopyridine compounds as PAD inhibitors 朱比兰特埃皮帕德有限公司 2023-03-07 CN disclosed
EP-3697785-B1 IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS Jubilant Epipad LLC (US) 2022-12-28 EP disclosed
US-20020161237-A1 Dehydroamino acids HOFFMANN-LA ROCHE INC. 2002-10-31 US disclosed
WO-2002055491-A2 1,2-DISUBSTITUTED CYCLIC INHIBITORS OF MATRIX METALLORPROTEASES AND TNF-$g(a) BRISTOL MYERS SQUIBB COMPANY P (US) 2002-07-18 WO disclosed
US-6403632-B1 CYCLIC AMIDE DERIVATIVE BRISTOL MYERS SQUIBB PHARMA CO (US) 2002-06-11 US disclosed
EP-1186604-A1 BENZAZEPINE DERIVATIVES, PROCESS FOR THE PREPARATION OF THE SAME AND USES THEREOF Takeda Chemical Industries, Ltd. (JP) 2002-03-13 EP disclosed
EP-1162196-A1 FUSED-RING COMPOUNDS AND USE THEREOF AS DRUGS JAPAN TOBACCO INC. (JP) 2001-12-12 EP disclosed
WO-2001058853-A1 DEHYDROAMINO ACIDS F. HOFFMANN-LA ROCHE AG (CH) 2001-08-16 WO disclosed
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 US disclosed
CN-1272841-A Novel lactam metalloprotease inhibitors DU PONT PHARM CO (US) 2000-11-08 CN disclosed
US-6057336-A ANTIINFLAMMATORY AGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-02 US disclosed
WO-1998050031-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO disclosed