Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807006 | 0.79 | NPC1 (0.66) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19911581 | 0.79 | NPC1 (1.00) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19911612 | 0.79 | NPC1 (0.66) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18167005 | 0.79 | KDM4E (0.66) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19848194 | 0.79 | NPC1 (0.60) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18393241 | 0.79 | SMN1; SMN2 (0.54) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL165333 | 0.77 | SMN1; SMN2 (0.71) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13610401 | 0.76 | KDM4E (0.60) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19848254 | 0.76 | L3MBTL1 (0.60) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9524603 | 0.76 | L3MBTL1 (0.60) | NPC1KDM4EL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296873-B1 | DIRECT POSITIVE DIMETHINE CYANINE DYES CONTAINING 1-ARYL-2-HETEROARYL INDOLE NUCLEUS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| US-4241168-A | TWO-EQUIVALENT MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-23 | — | — | US | disclosed |
| US-4220470-A | TWO-EQUIVALENT COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |
| US-4040835-A | Two-equivalent magenta couplers with amido coupling-off groups | FUJI PHOTO FILM CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |