Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 4/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794621 | 0.79 | LAP3 (0.33) | LAP3ANPEPERAP1TRPM8MMP1 | |
| SCHEMBL11330665 | 0.79 | ANPEP (0.37) | LAP3ANPEPERAP1TDP1TRPM8 | |
| SCHEMBL15185856 | 0.79 | CTSA (0.43) | CTSAACHELAP3ANPEPERAP1 | |
| SCHEMBL27621473 | 0.77 | — | — | |
| SCHEMBL4623205 | 0.77 | — | — | |
| SCHEMBL2478306 | 0.77 | — | — | |
| SCHEMBL3625655 | 0.76 | LAP3 (0.38) | LAP3ANPEPERAP1 | |
| SCHEMBL3083684 | 0.75 | KDM4E (0.43) | CTSAACHELAP3ANPEPERAP1 | |
| SCHEMBL17626471 | 0.75 | CTSA (0.40) | CTSAACHELAP3KDM4EALDH1A1 | |
| SCHEMBL17626591 | 0.75 | CTSA (0.40) | CTSAACHELAP3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |