SCHEMBL9505994

SCHEMBL9505994

CC(=O)Nc1nc(O)cc(O)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.57
ADORA3 P0DMS8 3/20 0.52
ADORA1 P30542 1/20 0.52
POLB P06746 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.43
ALDH1A1 P00352 3/20 0.42
RAB9A P51151 2/20 0.42
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
GLA P06280 1/20 0.41
TNNI3 P19429 1/20 0.41
TNNT2 P45379 1/20 0.41
TNNC1 P63316 1/20 0.41
RUNX1 Q01196 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13401387 0.88 CYP1A2 (0.50) CYP1A2ADORA3ADORA1POLBCYP2C9
SCHEMBL11171033 0.86 CYP1A2 (0.49) CYP1A2ADORA3ADORA1POLBCYP2C9
SCHEMBL3299561 0.80 POLB (0.62) CYP1A2ADORA3ADORA1POLBCYP2C9
SCHEMBL9505940 0.77 PEPD (0.40) CYP1A2ALDH1A1MAPTMEN1KMT2A
SCHEMBL11463095 0.77 CYP1A2 (0.70) CYP1A2ADORA3ADORA1POLBCYP2C9
SCHEMBL4552543 0.77 L3MBTL1 (0.59) CYP1A2ADORA3ADORA1POLBCYP2C9
SCHEMBL11176651 0.76 CYP1A2 (0.55) CYP1A2ADORA3ADORA1POLBCYP2C9
SCHEMBL140276 0.76 CYP1A2 (0.55) CYP1A2ADORA3ADORA1POLBCYP2C9
SCHEMBL5629171 0.75 KDM4E (0.46) CYP1A2ADORA3ADORA1POLBLMNA
SCHEMBL7050966 0.72 LCK (0.40) RAB9AMEN1KMT2ANPC1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
EP-0093306-B1 METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS BAYER AG (DE) 1986-09-24 EP disclosed
US-4421601-A LACQUERS, INKS, PAINTS, TEXTILES, PAPER BAYER AKTIENGESELLSCHAFT (DE) 1983-12-20 US disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed