Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464053 | 0.97 | MAPT (0.46) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9503752 | 0.94 | MAPT (0.49) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8915090 | 0.94 | MAPT (0.51) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8917111 | 0.93 | MAPT (0.50) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8916541 | 0.93 | MAPT (0.50) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8916551 | 0.93 | MAPT (0.50) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8917108 | 0.93 | MAPT (0.50) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9503776 | 0.91 | NPC1 (0.46) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL9455778 | 0.89 | MAPT (0.51) | MAPTNPC1LMNANFKB1NFKB2 | |
| SCHEMBL8917247 | 0.88 | ADRB2 (0.58) | MAPTNPC1LMNASMN1; SMN2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348873-B1 | FERROELECTRIC LIQUID-CRYSTALLINE POLYMER AND EPOXIDE USABLE FOR PREPARING THE FERROELECTRIC LIQUID-CRYSTALLINE POLYMER | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4954600-A | HIGH SPEED DISPLAY | IDEMITSU KOSAN CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |