SCHEMBL9506153

SCHEMBL9506153

CC[C@@H](C)[C@@H](N)C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.55
ENPEP Q07075 16/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27313721 1.00 ECE1 (0.55) ECE1ENPEP
SCHEMBL9437456 1.00 ECE1 (0.55) ECE1ENPEP
SCHEMBL9437463 1.00 ECE1 (0.55) ECE1ENPEP
SCHEMBL29352074 0.92 ECE1 (0.48) ECE1ENPEP
SCHEMBL31590256 0.90 ENPEP (0.47) ECE1ENPEP
SCHEMBL9437437 0.89 ENPEP (0.55) ENPEP
SCHEMBL9437455 0.89 ENPEP (0.55) ENPEP
SCHEMBL9437460 0.89 ENPEP (0.55) ENPEP
SCHEMBL9437439 0.89 ENPEP (0.55) ENPEP
SCHEMBL17399494 0.87 ECE1 (0.43) ECE1ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0288897-B1 ENKASTINES: GLYCOPEPTIDES WITH AN ENKEPHALINASE-INHIBITING EFFECT, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-11 EP disclosed
EP-0288897-A2 Enkastines: glycopeptides with an enkephalinase-inhibiting effect, process for their preparation and their pharmaceutical use HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-02 EP disclosed