Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83018 | 0.87 | LMNA (0.52) | TDP1LMNAHKDC1TAAR1MIF | |
| SCHEMBL30034760 | 0.87 | LMNA (0.52) | TDP1LMNAHKDC1TAAR1MIF | |
| Hydrochloric Acid SCHEMBL28970405 | 0.85 | LMNA (0.50) | CYP3A4TDP1LMNAHKDC1TAAR1 | |
| SCHEMBL5006192 | 0.85 | LMNA (0.50) | TDP1LMNAHKDC1TAAR1MIF | |
| SCHEMBL7919519 | 0.83 | CYP3A4 (0.57) | CYP3A4TDP1LMNAESR1ESR2 | |
| SCHEMBL9132814 | 0.77 | CYP3A4 (0.55) | CYP3A4TDP1LMNAESR1ESR2 | |
| SCHEMBL30692060 | 0.76 | CYP3A4 (0.48) | CYP3A4TDP1ESR1ESR2TAAR1 | |
| SCHEMBL22023051 | 0.75 | CYP3A4 (0.67) | CYP3A4TDP1LMNAESR1ESR2 | |
| SCHEMBL21084294 | 0.75 | CYP3A4 (0.67) | CYP3A4TDP1LMNAESR1ESR2 | |
| Bromoethane SCHEMBL43961 | 0.75 | TDP1 (0.67) | CYP3A4TDP1LMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |