Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505521 | 0.86 | GAA (0.67) | GAATDP1L3MBTL1EPHX2SMPD1 | |
| SCHEMBL9502190 | 0.84 | GAA (0.64) | GAATDP1L3MBTL1EPHX2SMPD1 | |
| SCHEMBL9503796 | 0.82 | GAA (0.59) | GAATDP1L3MBTL1EPHX2SMPD1 | |
| SCHEMBL9503808 | 0.82 | GAA (0.59) | GAATDP1L3MBTL1EPHX2SMPD1 | |
| SCHEMBL9505648 | 0.81 | GAA (0.73) | GAATDP1L3MBTL1EPHX2HDAC1 | |
| SCHEMBL9503820 | 0.81 | GAA (0.73) | GAATDP1L3MBTL1EPHX2HDAC1 | |
| SCHEMBL9503771 | 0.80 | GAA (0.71) | GAATDP1L3MBTL1EPHX2HDAC1 | |
| SCHEMBL9506191 | 0.80 | GAA (0.71) | GAATDP1L3MBTL1EPHX2HDAC1 | |
| SCHEMBL9506185 | 0.79 | GAA (0.70) | GAATDP1L3MBTL1EPHX2HDAC1 | |
| SCHEMBL9502168 | 0.78 | GAA (0.64) | GAATDP1L3MBTL1EPHX2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |