Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055579 | 0.86 | CTSK (0.55) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL11785916 | 0.84 | CTSK (0.53) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL10912953 | 0.83 | CTSK (0.52) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL17550877 | 0.82 | CTSK (0.49) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL10658684 | 0.81 | NPC1 (0.55) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL9696685 | 0.81 | TSHR (0.55) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL10869477 | 0.81 | CTSK (0.51) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL19385458 | 0.81 | CTSK (0.49) | CTSKCTSLCTSBNPC1RAB9A | |
| SCHEMBL1838248 | 0.81 | SLC6A2 (0.54) | CTSKCTSLCTSBCTSHNPC1 | |
| SCHEMBL6826673 | 0.81 | TSHR (0.53) | CTSKCTSLCTSBCTSHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410214-B1 | PROCESS FOR THE PREPARATION OF N,N-DISUBSTITUTED MONO- AND OLIGOURETHANES | BAYER AG (DE) | 1993-08-18 | — | — | EP | disclosed |
| EP-0410214-A1 | Process for the preparation of N,N-disubstituted Mono- and Oligourethanes | BAYER AG (DE) | 1991-01-30 | — | — | EP | disclosed |