Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507851 | 0.91 | KDM4E (0.45) | CYP11B1CYP11B2KDM4EALDH1A1HPGD | |
| SCHEMBL9506551 | 0.90 | KDM4E (0.50) | CYP11B1CYP11B2KDM4EALDH1A1HPGD | |
| SCHEMBL9506414 | 0.88 | KDM4E (0.50) | CYP11B1CYP11B2KDM4EALDH1A1HPGD | |
| SCHEMBL24076492 | 0.87 | CYP11B1 (0.50) | CYP11B1CYP11B2PDE3AKDM4EALDH1A1 | |
| SCHEMBL9506037 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9507799 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9506105 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9506393 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9506339 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9506375 | 0.87 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | claimed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | claimed |
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | disclosed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | disclosed |