Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18122821 | 0.78 | KDM4E (0.63) | KDM4EKMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL7824150 | 0.77 | CYP2C19 (0.39) | ALDH1A1SMN1; SMN2TSHRLMNABLM | |
| SCHEMBL1957150 | 0.76 | KDM4E (0.36) | KDM4EKMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL4280661 | 0.75 | KDM4E (0.39) | KDM4EKMT2AALDH1A1SMN1; SMN2OPRL1 | |
| SCHEMBL13448658 | 0.75 | KDM4E (0.65) | KDM4EKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL32690599 | 0.75 | KDM4E (0.39) | KDM4EKMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL12869546 | 0.75 | ALDH1A1 (0.49) | KDM4EKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL13448704 | 0.75 | ALDH1A1 (0.40) | KDM4EKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4928521 | 0.73 | KDM4E (0.38) | KDM4EKMT2AALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL24946123 | 0.73 | KDM4E (0.38) | KDM4EKMT2AALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330247-B1 | N-HYDROXY-ALPHA-AMINO ACIDS, AMIDES AND OTHER DERIVATIVES THEREOF | DSM N.V. (NL) | 1993-07-07 | — | — | EP | disclosed |
| US-5101036-A | PROCESS FOR THE PREPARATION OF N-HYDROXY-ALPHA-AMINO ACID AMIDES | STAMICARBON B.V. (NL) | 1992-03-31 | — | — | US | disclosed |