Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504535 | 0.95 | SLC6A5 (0.49) | SLC6A5GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL55497 | 0.88 | GRIN2D (0.48) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7309113 | 0.85 | EPHX1 (0.57) | EPHX1CASP2 | |
| SCHEMBL8393792 | 0.85 | EPHX1 (0.57) | EPHX1CASP2 | |
| SCHEMBL8392175 | 0.85 | EPHX1 (0.57) | EPHX1CASP2 | |
| SCHEMBL4561173 | 0.82 | EPHX1 (0.54) | DPP7EPHX1CASP2 | |
| SCHEMBL7310215 | 0.81 | EPHX1 (0.57) | EPHX1CASP2 | |
| SCHEMBL8391466 | 0.81 | EPHX1 (0.57) | EPHX1CASP2 | |
| SCHEMBL8391878 | 0.81 | EPHX1 (0.57) | EPHX1CASP2 | |
| SCHEMBL8393481 | 0.81 | EPHX1 (0.55) | EPHX1CASP2ACHEMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434354-B1 | SEPARATION MATERIAL FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF | KURITA WATER INDUSTRIES LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| EP-0434354-A1 | Separation material for blood coagulation factor, preparation and use thereof | KURITA WATER INDUSTRIES LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |