Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 10/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506406 | 0.96 | MAPT (0.50) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9506395 | 0.95 | HSD17B10 (0.52) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9506398 | 0.95 | HSD17B10 (0.52) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9506494 | 0.95 | HSD17B10 (0.52) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9507836 | 0.95 | HSD17B10 (0.52) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9506648 | 0.95 | HSD17B10 (0.52) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9506361 | 0.95 | HSD17B10 (0.52) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9509921 | 0.95 | HSD17B10 (0.52) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9506512 | 0.92 | RAB9A (0.40) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL9511175 | 0.88 | RARB (0.41) | RAB9ASMN1; SMN2ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | claimed |
| US-4883609-A | LIQUID CRYSTALS | SEIKO EPSON CORPORATION (JP) | 1989-11-28 | — | — | US | claimed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | claimed |
| EP-0317175-B1 | PYRIMIDINE DERIVATIVES | SEIKO EPSON CORPORATION (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-4883609-A | LIQUID CRYSTALS | SEIKO EPSON CORPORATION (JP) | 1989-11-28 | — | — | US | disclosed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | disclosed |