Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 5/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 4/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12345872 | 0.84 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL14412626 | 0.80 | GRIN2D (0.34) | — | |
| SCHEMBL31672568 | 0.79 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL16017830 | 0.79 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL3134815 | 0.79 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL1817193 | 0.77 | SLC7A5 (0.38) | SLC7A5DPP4 | |
| SCHEMBL844430 | 0.76 | TSHR (0.31) | TSHR | |
| SCHEMBL13144609 | 0.76 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL9621432 | 0.74 | SLC7A5 (0.45) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL9506655 | 0.74 | SLC7A5 (0.45) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041047-A2 | Dioxide compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-12-02 | — | — | EP | claimed |
| EP-0278911-B1 | BICYCLIC BETA-LACTAM CARBOXYLIC ACIDS | CIBA-GEIGY AG (CH) | 1993-08-04 | — | — | EP | disclosed |
| EP-0246187-B1 | 2-PYRIDYL PENEM COMPOUNDS | CIBA-GEIGY AG (CH) | 1992-02-05 | — | — | EP | disclosed |
| US-4965260-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0166697-B1 | AROYL SUBSTITUTED DIHYDRO-1,4-THIAZINES | CIBA-GEIGY AG (CH) | 1990-05-09 | — | — | EP | disclosed |
| US-4826832-A | BACTERICIDES | CIBA-GEIGY CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0297042-A1 | Substituted penem compounds | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | disclosed |
| US-4794109-A | 6-hydroxy-lower alkylpenem compounds, pharmaceutical preparations that contain these compounds, and the use of the latter | CIBA-GEIGY CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0278911-A1 | Bicyclic beta-lactam carboxylic acids | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |
| EP-0275233-A1 | 2-Heterocyclylalkyl-2-penem compounds | CIBA-GEIGY AG (CH) | 1988-07-20 | — | — | EP | disclosed |
| EP-0046734-A2 | Aminohydroxyphenyl derivatives of cephalosporins, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1982-03-03 | — | — | EP | disclosed |
| US-4313945-A | 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping | CIBA-GEIGY CORPORATION (US) | 1982-02-02 | — | — | US | disclosed |
| EP-0041047-A2 | Dioxide compounds, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-12-02 | — | — | EP | disclosed |
| EP-0037797-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application | CIBA-GEIGY AG (CH) | 1981-10-14 | — | — | EP | disclosed |
| EP-0031794-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1981-07-08 | — | — | EP | disclosed |
| EP-0025017-A1 | Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter | CIBA-GEIGY AG (CH) | 1981-03-11 | — | — | EP | disclosed |
| EP-0022245-A2 | Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-01-14 | — | — | EP | disclosed |
| EP-0016900-A1 | Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use | CIBA-GEIGY AG (CH) | 1980-10-15 | — | — | EP | disclosed |
| EP-0016296-A1 | Cephalosporin derivatives, process for their preparation, compositions containing them, and intermediates and their preparation | CIBA-GEIGY AG (CH) | 1980-10-01 | — | — | EP | disclosed |
| EP-0000500-A2 | Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |