SCHEMBL12345872

SCHEMBL12345872

CC(C)CC(N)C(=O)OCOC(=O)C(N)CC(C)C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
SLC1A3 P43003 3/20 0.43
SLC1A2 P43004 3/20 0.43
ANPEP P15144 7/20 0.41
RNPEP Q9H4A4 4/20 0.41
DNPEP Q9ULA0 2/20 0.41
LAP3 P28838 4/20 0.38
ERAP1 Q9NZ08 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
SLC1A1 P43005 2/20 0.36
LARS1 Q9P2J5 1/20 0.35
CACNA2D1 P54289 2/20 0.34
CACNB3 P54284 1/20 0.34
CACNA1C Q13936 1/20 0.34
PGR P06401 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
CACNA2D2 Q9NY47 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16017830 0.94 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL31672568 0.89 SLC7A5 (0.50) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL13144609 0.86 SLC7A5 (0.56) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL9506655 0.84 SLC7A5 (0.45) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL9621432 0.84 SLC7A5 (0.45) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL9506659 0.84 SLC7A5 (0.45) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL10403593 0.84 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL133092 0.84 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7359844 0.84 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL10403594 0.84 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2ANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9056155-B1 Coatings having an elastic primer layer ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2015-06-16 US disclosed
US-8865189-B2 Poly(ester amide)-based drug delivery systems ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2014-10-21 US disclosed
US-20130129794-A1 Poly(Ester Amide)-Based Drug Delivery Systems ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2013-05-23 US disclosed
US-8389044-B2 Poly(ester amide)-based drug delivery systems with controlled release rate and morphology ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2013-03-05 US disclosed
US-8377499-B2 Methods of forming Poly(ester amide)-based drug delivery systems with controlled release rate and morphology ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2013-02-19 US disclosed
US-8377107-B2 Poly(ester amide)-based drug delivery systems with controlled release rate and morphology ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2013-02-19 US disclosed
US-20110200660-A1 POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2011-08-18 US disclosed
US-20110151104-A1 POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2011-06-23 US disclosed
US-7910152-B2 Poly(ester amide)-based drug delivery systems with controlled release rate and morphology ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2011-03-22 US disclosed
US-7749263-B2 Poly(ester amide) filler blends for modulation of coating properties ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2010-07-06 US disclosed
US-20080206306-A1 POLY(ESTER AMIDE) BLOCK COPOLYMERS ABBOTT CARDIOVASCULAR SYSTEMS INC. 2008-08-28 US disclosed
US-20080175886-A1 Blends Of Poly(Ester Amide) Polymers ADVANCED CARDIOVASCULAR SYSTEM INC. (US) 2008-07-24 US disclosed
US-20080177008-A1 Blends Of Poly(Ester Amide) Polymers ADVANCED CARDIOVASCULAR SYSTEMS INC. (US) 2008-07-24 US disclosed
US-20080167712-A1 POLY(ESTER AMIDE) FILLER BLENDS FOR MODULATION OF COATING PROPERTIES ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2008-07-10 US disclosed
US-7390497-B2 Poly(ester amide) filler blends for modulation of coating properties ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2008-06-24 US disclosed
US-7365133-B2 Blends of poly(ester amide) polymers ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2008-04-29 US disclosed
US-20080095918-A1 Coating construct with enhanced interfacial compatibility ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2008-04-24 US disclosed
US-20070202147-A1 Poly(ester amide)-based drug delivery systems with controlled release rate and morphology ABBOTT CARDIOVASCULAR SYSTEMS INC. 2007-08-30 US disclosed
US-20070135909-A1 Adhesion polymers to improve stent retention ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2007-06-14 US disclosed
US-20070093617-A1 Blends of poly(ester amide) polymers ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2007-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110200660-A1 POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY PAM, PUF60, ACMSD SLC7A5 2035/4885SLC1A3 991/4885SLC1A2 1035/4885
US-20080177008-A1 Blends Of Poly(Ester Amide) Polymers TAAR5, TAAR1, PAM SLC7A5 4046/4885SLC1A3 4562/4885SLC1A2 4637/4885
US-20080175886-A1 Blends Of Poly(Ester Amide) Polymers BMP2, NAAA, PHOSPHO1 SLC7A5 4140/4885SLC1A3 2249/4885SLC1A2 2417/4885
US-20070202147-A1 Poly(ester amide)-based drug delivery systems with controlled release rate and morphology PUF60, PAM, ACMSD SLC7A5 1557/4885SLC1A3 662/4885SLC1A2 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.