Isobutanol

Isobutanol

SCHEMBL9506669

CC(C)CO.c1cc2cc-2c1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.47
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
ESR1 P03372 1/20 0.44
APP P05067 1/20 0.42
GABRA1 P14867 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRB2 P47870 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2E1 P05181 1/20 0.39
CYP2C8 P10632 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP4B1 P13584 1/20 0.39
CYP2B6 P20813 1/20 0.39
CYP3A5 P20815 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Alcohol SCHEMBL6748246 0.80 MEN1 (0.50) TSHRKMT2AMEN1ESR1APP
Alcohol SCHEMBL4352265 0.80
SCHEMBL28929274 0.80
SCHEMBL29152365 0.80 PTGS2 (0.50) TSHRKMT2AMEN1CYP2C9CYP1A2
Isopropyl Alcohol SCHEMBL28748226 0.78 MEN1 (0.48) TSHRKMT2AMEN1ESR1APP
Isobutanol SCHEMBL27627626 0.77 TSHR (0.60) TSHRESR1GABRA1GABRG2GABRB3
Butanol SCHEMBL28098196 0.77 TSHR (0.50) TSHRKMT2AMEN1ESR1APP
Methyl Alcohol SCHEMBL27613845 0.76
Propanol SCHEMBL7877650 0.76 MEN1 (0.46) KMT2AMEN1ESR1APPCYP3A4
Isopropylamine SCHEMBL7096169 0.75 CYP2A6 (0.44) KMT2AMEN1ESR1APPCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113056547-A Jasmine alcohol 西姆莱斯有限公司 2021-06-29 CN claimed
EP-0294557-B1 PROCESS FOR THE PREPARATION OF 3-PHENYL-2-METHYLPROPANOL AND ITS PARA-SUBSTITUTED ALKYLIC DERIVATIVES HÜLS AKTIENGESELLSCHAFT (DE) 1992-07-08 EP claimed
CN-109311789-B Process for preparing 2, 3-unsaturated alcohols 巴斯夫欧洲公司 2023-04-04 CN disclosed
CN-115551825-A Lilac type aromatic compound 西姆莱斯有限公司 2022-12-30 CN disclosed
CN-113056547-A Jasmine alcohol 西姆莱斯有限公司 2021-06-29 CN disclosed
CN-112969444-A Use of 1-ethyl-4, 4-dimethylcyclohexane derivatives as fragrance substances 西姆莱斯有限公司 2021-06-15 CN disclosed
CN-112969774-A Perfuming ingredients with muguet fragrance 西姆莱斯有限公司 2021-06-15 CN disclosed
CN-105939761-B Delayed release perfume composition 雅芳产品公司 2020-10-23 CN disclosed
CN-109311789-A The method for preparing 2,3- unsaturated alcohol 巴斯夫欧洲公司 2019-02-05 CN disclosed
CN-108601837-A extended release fragrance composition 雅芳产品公司 2018-09-28 CN disclosed
CN-105939761-A Extended release fragrance compositions 雅芳产品公司 2016-09-14 CN disclosed
EP-0358088-B1 PROCESS FOR THE PREPARATION OF 3-ARYL ISOBUTANOLS BASF Aktiengesellschaft (DE) 1993-06-23 EP disclosed
US-4987270-A From benzylalcohol or derivative and n-propanol; alkali metal hydroxide catalyst BASF AKTIENGESELLSCHAFT (DE) 1991-01-22 US disclosed
EP-0358088-A2 Process for the preparation of 3-aryl isobutanols BASF Aktiengesellschaft (DE) 1990-03-14 EP disclosed
EP-0294557-A2 Process for the preparation of 3-phenyl-2-methylpropanol and its para-substituted alkylic derivatives HÜLS AKTIENGESELLSCHAFT (DE) 1988-12-14 EP disclosed