Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | STAT6 | P42226 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242097 | 0.92 | ESR1 (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL28927408 | 0.92 | ELANE (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL13595800 | 0.92 | ESR1 (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL12021697 | 0.92 | LMNA (0.52) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL2691203 | 0.91 | ELANE (0.53) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL13133162 | 0.88 | ESR1 (0.63) | LMNAMAPTPOLBPKMELANE | |
| Phenol SCHEMBL10624777 | 0.88 | ELANE (0.54) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL1714626 | 0.87 | LMNA (0.59) | LMNAMAPTPOLBPKMELANE | |
| SCHEMBL715235 | 0.86 | LMNA (0.53) | LMNAMAPTPOLBPKMELANE | |
| Hydrogen Peroxide SCHEMBL9578945 | 0.85 | LMNA (0.57) | LMNAMAPTPOLBPKMELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892912-A | DEPOLYMERIZATION THEN POLYMERIZING FRAGMENTS, ELASTICITY, MECHANICAL STRENGTH | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1990-01-09 | — | — | US | claimed |
| US-20140186872-A1 | BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS (FR) | 2014-07-03 | — | — | US | disclosed |
| US-20140186872-A1 | BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS (FR) | 2014-07-03 | — | — | US | disclosed |
| WO-2012168885-A2 | BISACODYL AND ANALOGUES AS DRUGS FOR TREATING CANCER | UNIVERSITÉ DE STRASBOURG (FR) | 2012-12-13 | — | — | WO | disclosed |
| EP-0321691-B1 | PROCESS FOR PRODUCING AROMATIC POLYESTER | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4892912-A | DEPOLYMERIZATION THEN POLYMERIZING FRAGMENTS, ELASTICITY, MECHANICAL STRENGTH | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0321691-A2 | Process for producing aromatic polyester | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1989-06-28 | — | — | EP | disclosed |
| EP-0212482-B1 | PROCESS FOR OBTAINING NEGATIVE IMAGES FROM POSITIVE PHOTORESISTS | HOECHST CELANESE CORPORATION (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0106156-B1 | LIGHT-SENSITIVE COMPOSITION | HOECHST CELANESE CORPORATION (US) | 1988-12-21 | — | — | EP | disclosed |
| EP-0212482-A2 | Process for obtaining negative images from positive photoresists | HOECHST CELANESE CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
| EP-0061150-B1 | LIGHT-SENSITIVE POLYCONDENSATION PRODUCT, PROCESS FOR ITS PREPARATION AND LIGHT-SENSITIVE RECORDING MATERIAL CONTAINING THE SAME | AMERICAN HOECHST CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0106156-A2 | Light-sensitive composition | HOECHST CELANESE CORPORATION (US) | 1984-04-25 | — | — | EP | disclosed |
| US-4436804-A | Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith | AMERICAN HOECHST CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4435496-A | WITH FREE RADICAL PHOTOSENSITIZER | AMERICAN HOECHST CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |
| EP-0061150-A1 | Light-sensitive polycondensation product, process for its preparation and light-sensitive recording material containing the same | AMERICAN HOECHST CORPORATION (US) | 1982-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140186872-A1 | BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER | CCND1, DEGS1, MCL1 | LMNA 1234/4885MAPT 3710/4885POLB 1088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.