SCHEMBL9506885

SCHEMBL9506885

Cc1cc(=N)n(-c2ccccc2)[nH]1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPT P10636 6/20 0.41
KDM4E B2RXH2 5/20 0.41
KMT2A Q03164 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
GAA P10253 5/20 0.41
HTT P42858 4/20 0.41
MEN1 O00255 2/20 0.41
LMNA P02545 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 2/20 0.40
GFER P55789 1/20 0.40
ALOX15 P16050 1/20 0.40
BLM P54132 1/20 0.40
ATM Q13315 1/20 0.40
RECQL P46063 1/20 0.39
AURKA O14965 1/20 0.38
DAPK3 O43293 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11688550 0.98 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPTKDM4EKMT2A
SCHEMBL10949906 0.77 ALDH1A1 (0.44) ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2
SCHEMBL34121 0.76 ALDH1A1 (0.68) ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2
SCHEMBL5425653 0.76 ALDH1A1 (0.68) ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2
SCHEMBL6740143 0.76 ALDH1A1 (0.55) ALDH1A1HSD17B10MAPTKDM4EKMT2A
SCHEMBL20441077 0.76 ALDH1A1 (0.42) ALDH1A1HSD17B10MAPTKDM4EKMT2A
SCHEMBL9150171 0.76 ALDH1A1 (0.68) ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2
SCHEMBL8040128 0.74 ALDH1A1 (0.39) ALDH1A1HSD17B10MAPTKDM4EKMT2A
SCHEMBL10945886 0.74 KDM4E (0.66) ALDH1A1MAPTKDM4ESMN1; SMN2
Methyl Alcohol SCHEMBL1028813 0.73 MAPT (0.69) ALDH1A1MAPTKDM4EKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0297397-B1 PREPARATION OF DIAZO AND AZO COMPOUNDS BAYER AG (DE) 1993-08-04 EP disclosed
US-4942225-A Preparation of diazo and azo compounds using azidoformamidium salts BAYER AKTIENGESELLSCHAFT (DE) 1990-07-17 US disclosed
US-4918183-A Monoazo dyes, process for their preparation, and the use thereof CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
US-4906740-A Monoazo dyes containing as the azo component A phenylsulfonylphenyl radical CIBA-GEIGY CORPORATION (US) 1990-03-06 US disclosed
EP-0297397-A2 Preparation of diazo and azo compounds BAYER AG (DE) 1989-01-04 EP disclosed
EP-0102325-B1 MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-01-21 EP disclosed
EP-0093306-B1 METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS BAYER AG (DE) 1986-09-24 EP disclosed
EP-0101664-B1 MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-06-04 EP disclosed
EP-0101408-B1 MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-05-07 EP disclosed
US-4556707-A DYEING CELLULOSE FIBERS AND POLYAMIDE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1985-12-03 US disclosed
US-4540776-A Reactive fluorotriazinylaminonaphthotriazolyphenylazopyridone or pyrimidone dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1985-09-10 US disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed
US-4354968-A Azo reactive dyestuffs having an aryl-triazinyl-aryl diazo component BAYER AKTIENGESELLSCHAFT (DE) 1982-10-19 US disclosed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed