Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504771 | 0.90 | THRA (0.54) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504622 | 0.85 | THRA (0.52) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9508783 | 0.85 | THRA (0.52) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9508886 | 0.81 | THRA (0.52) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9836351 | 0.81 | THRA (0.48) | THRATHRBMEN1KMT2A | |
| SCHEMBL9508884 | 0.81 | THRA (0.51) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL27671411 | 0.81 | THRA (0.53) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504721 | 0.81 | THRA (0.63) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL9504824 | 0.80 | THRA (0.50) | THRATHRBRARBMEN1ALDH1A1 | |
| SCHEMBL10533853 | 0.79 | THRA (0.60) | THRATHRBRARBMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |