Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GNA15 | P30679 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506962 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9506075 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9508951 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9508296 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9506896 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9506886 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9508944 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9506072 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9508304 | 1.00 | TNNC1 (0.49) | TNNC1ALDH1A1DUSP3PTPN7KDM4E | |
| SCHEMBL9506877 | 0.94 | TNNC1 (0.42) | TNNC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |