Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29518370 | 0.86 | TSHR (0.55) | TSHRALDH1A1CA5ACA5BTDP1 | |
| Sulfuric Acid SCHEMBL1193805 | 0.86 | — | — | |
| Sulfuric Acid SCHEMBL9754869 | 0.86 | TSHR (0.55) | TSHRALDH1A1CA5ACA5BTDP1 | |
| Acetaldehyde SCHEMBL662140 | 0.86 | — | — | |
| Acetaldehyde SCHEMBL20959767 | 0.86 | — | — | |
| Sulfuric Acid SCHEMBL84046 | 0.86 | — | — | |
| Sulfuric Acid SCHEMBL13506810 | 0.86 | TSHR (0.55) | TSHRALDH1A1CA5ACA5BTDP1 | |
| Acetaldehyde SCHEMBL3400941 | 0.86 | — | — | |
| Sulfuric Acid SCHEMBL21624984 | 0.86 | TSHR (0.55) | TSHRALDH1A1CA5ACA5BTDP1 | |
| Sulfuric Acid SCHEMBL11226653 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996146-A | CATIONIC POLYMER, ANIONIC AND AMPHOTERIC DETERGENTS | WARNER-LAMBERT COMPANY (US) | 1976-12-07 | — | — | US | claimed |
| EP-0258988-B1 | MASTIC AND CAULKING COMPOSITIONS AND COMPOSITE ARTICLES | ROHM AND HAAS COMPANY (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5135813-A | Mastic and caulking composite articles | UNION OIL COMPANY OF CALIFORNIA (US) | 1992-08-04 | — | — | US | disclosed |
| US-5120607-A | Latex, zinc-containing pigment, polyphosphate | UNION OIL COMPANY OF CALIFORNIA (US) | 1992-06-09 | — | — | US | disclosed |
| US-5073445-A | Mastic and caulking compositions and composite articles | UNION OIL COMPANY OF CALIFORNIA (US) | 1991-12-17 | — | — | US | disclosed |
| US-5055511-A | Wet adhesion; organoacyl or cyano containing polymer, zinc compound, polyphosphate | UNION OIL COMPANY OF CALIFORNIA (US) | 1991-10-08 | — | — | US | disclosed |
| US-4855349-A | Mastic and caulking compositions and composite articles | UNION OIL COMPANY OF CALIFORNIA (US) | 1989-08-08 | — | — | US | disclosed |
| EP-0258988-A2 | Mastic and caulking compositions and composite articles | ROHM AND HAAS COMPANY (US) | 1988-03-09 | — | — | EP | disclosed |