Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9507030 | 0.91 | ALOX5 (0.64) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9584634 | 0.91 | ALOX5 (0.64) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| Water SCHEMBL9588688 | 0.90 | ALOX5 (0.63) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9332072 | 0.86 | ALOX5 (0.81) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7801687 | 0.86 | ALOX5 (0.81) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2683757 | 0.86 | ALOX5 (0.81) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10349746 | 0.85 | ALOX5 (0.80) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7801682 | 0.84 | ALOX5 (0.66) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10349747 | 0.84 | ALOX5 (0.66) | ALOX5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9589932 | 0.84 | ALOX5 (0.66) | ALOX5PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250693-A | Lipoxygenase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | claimed |
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |