Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401700 | 1.00 | TAAR1 (0.55) | TAAR1TBXAS1HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7266355 | 0.99 | TBXAS1 (0.54) | TAAR1TBXAS1HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL11261045 | 0.97 | TBXAS1 (0.53) | TAAR1TBXAS1HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL10848541 | 0.97 | TBXAS1 (0.53) | TAAR1TBXAS1HDAC8HDAC3HDAC4 | |
| SCHEMBL11107735 | 0.84 | CA12 (0.49) | TAAR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL10845162 | 0.83 | CA12 (0.55) | TAAR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL11260195 | 0.83 | CA12 (0.55) | TAAR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL11476379 | 0.82 | NPC1 (0.51) | TAAR1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL8319084 | 0.81 | TAAR1 (0.43) | TAAR1TBXAS1HDAC8HDAC3HDAC4 | |
| SCHEMBL7299851 | 0.80 | TAAR1 (0.62) | TAAR1LMNACYP2D6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556204-A1 | PHARMACEUTICAL COMPOSITION CONTAINING AN ACE INHIBITOR AND AN INHIBITOR OF THROMBOXANE A2 ACTIVITY FOR TREATING NEPHROPATHIES | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-08-25 | — | — | EP | disclosed |
| EP-0058079-A2 | 4-(1-Imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same | Kissei Pharmaceutical Co. Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |