SCHEMBL9507343

SCHEMBL9507343

CC([C]=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766798 0.79
SCHEMBL17669761 0.72 LMNA (0.41) THRBLMNA
SCHEMBL2110240 0.71
SCHEMBL7588173 0.71
SCHEMBL17181222 0.71
SCHEMBL15668367 0.71
SCHEMBL16576108 0.71 LMNA (0.38) THRBLMNA
SCHEMBL16576097 0.71 LMNA (0.38) THRBLMNA
SCHEMBL13541921 0.71 LMNA (0.38) THRBLMNA
SCHEMBL16576084 0.71 LMNA (0.38) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549665-A1 POLY(FLUOROALKYL) SUGAR REAGENTS AND THEIR USE FOR SURFACE MODIFICATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-07 EP disclosed