⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377384 | 0.79 | — | — | |
| SCHEMBL978315 | 0.76 | ALDH1A1 (0.52) | — | |
| SCHEMBL780155 | 0.76 | CYP3A4 (0.54) | — | |
| Dimethyl Methylphosphonate SCHEMBL11598108 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL779857 | 0.73 | — | — | |
| SCHEMBL23521139 | 0.73 | ALDH1A1 (0.48) | — | |
| SCHEMBL2993962 | 0.73 | — | — | |
| SCHEMBL10410361 | 0.72 | LPAR3 (0.53) | — | |
| SCHEMBL11509865 | 0.72 | — | — | |
| SCHEMBL9661131 | 0.72 | ALDH1A1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1224382-A | — | — | None | — | — | JP | disclosed |
| EP-0336558-B1 | NOVEL ORGANIC PHOSPHOROUS DERIVATIVES AND MANUFACTURING PROCESSES THEREFOR | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0292918-B1 | PROCESS FOR PRODUCING PHOSPHINYLAMINO ACID DERIVATIVES | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |
| US-4906764-A | Process for producing phosphinylamino acid derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0336558-A1 | Novel organic phosphorous derivatives and manufacturing processes therefor | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-10-11 | — | — | EP | disclosed |
| JP-H01224382-A | ORGANIC PHOSPHORUS DERIVATIVE AND PRODUCTION THEREOF | NISSAN CHEM IND LTD | 1989-09-07 | — | — | JP | disclosed |
| EP-0292918-A1 | Process for producing phosphinylamino acid derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| US-4173578-A | Production of alkenyl phosphinic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |