Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | HPN | P05981 | 1/20 | 0.61 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692187 | 0.85 | ALOX15 (0.63) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL646924 | 0.85 | ALOX15 (0.63) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL9154935 | 0.84 | ALOX15 (0.57) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL10817343 | 0.83 | MAPT (0.61) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL8309159 | 0.82 | ALOX15 (0.59) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL8702044 | 0.82 | ALOX15 (0.59) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL8699143 | 0.81 | HPN (0.53) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL8834137 | 0.80 | MAPT (0.57) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL9328124 | 0.80 | ALOX15 (0.57) | MAPTALOX15HPNSIRT5PTGS1 | |
| SCHEMBL8493361 | 0.80 | ALOX15 (0.57) | MAPTALOX15HPNSIRT5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293895-B1 | PHENOLIC THIOETHERS AS INHIBITORS OF 5-LIPOXYGENASE | G.D. Searle & Co. (US) | 1993-08-11 | — | — | EP | claimed |
| US-4847305-A | Phenolic thioethers as inhibitors of 5-lipoxygenase | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | claimed |
| EP-0293895-A1 | Phenolic thioethers as inhibitors of 5-lipoxygenase | G.D. Searle & Co. (US) | 1988-12-07 | — | — | EP | claimed |
| EP-2952505-A1 | A hindered phenol compound, preparation thereof and use thereof as an antioxidant | China Petroleum & Chemical Corporation (CN) | 2015-12-09 | — | — | EP | disclosed |
| EP-0293895-B1 | PHENOLIC THIOETHERS AS INHIBITORS OF 5-LIPOXYGENASE | G.D. Searle & Co. (US) | 1993-08-11 | — | — | EP | disclosed |
| US-4847305-A | Phenolic thioethers as inhibitors of 5-lipoxygenase | G. D. SEARLE & CO. (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0293895-A1 | Phenolic thioethers as inhibitors of 5-lipoxygenase | G.D. Searle & Co. (US) | 1988-12-07 | — | — | EP | disclosed |