Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505448 | 0.88 | ALDH1A1 (0.55) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL279235 | 0.87 | TDP1 (0.71) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL10411865 | 0.83 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL279241 | 0.81 | TDP1 (0.63) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL279152 | 0.80 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL4428715 | 0.77 | TDP1 (0.65) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL278981 | 0.76 | TDP1 (0.58) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL2623391 | 0.76 | TDP1 (0.58) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL3148179 | 0.76 | TDP1 (0.67) | TDP1MEN1KMT2AALDH1A1TP53 | |
| SCHEMBL232507 | 0.75 | TDP1 (0.61) | TDP1MEN1KMT2AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295126-B1 | ARYLAMINE-CONTAINING POLYHYDROXY ETHER RESINS | XEROX CORPORATION (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4956440-A | Arylamine containing polyhydroxyether resins | XEROX CORPORATION (US) | 1990-09-11 | — | — | US | disclosed |
| US-4818650-A | Arylamine containing polyhydroxy ether resins and system utilizing arylamine containing polyhydroxyl ether resins | XEROX CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |