Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.69 |
| ▸ | RAB9A | P51151 | 9/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.69 |
| ▸ | RELA | Q04206 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691313 | 0.74 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL10094742 | 0.71 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL5836665 | 0.69 | ENPP3 (0.61) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL6170686 | 0.69 | MAPT (0.47) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL27844549 | 0.69 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL2088466 | 0.68 | ABL1 (0.60) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL8691309 | 0.68 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL9509414 | 0.67 | NR1H4 (0.55) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL19886565 | 0.67 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 | |
| SCHEMBL18610908 | 0.67 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2MAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1216981-A | — | — | None | — | — | JP | disclosed |
| EP-0325336-B1 | OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-08-04 | — | — | EP | disclosed |
| US-4929628-A | Oxadiazole compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B. V. (NL) | 1990-05-29 | — | — | US | disclosed |
| JP-H01216981-A | OXADIAZOLE COMPOUND, ITS PREPARATION AND ITS USE AS INSECTICIDE | SHELL INTERNATL RES MAATSCHAPPIJ BV | 1989-08-30 | — | — | JP | disclosed |
| EP-0325336-A1 | Oxadiazole compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-07-26 | — | — | EP | disclosed |