SCHEMBL9507873

SCHEMBL9507873

Oc1nc(-c2ccccc2Cl)no1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP7 Q9BQF6 3/20 0.52
ATM Q13315 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
CASP3 P42574 2/20 0.49
SENP8 Q96LD8 2/20 0.49
SENP6 Q9GZR1 2/20 0.49
TSHR P16473 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 1/20 0.48
GRM5 P41594 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14931632 0.82 ATM (0.56) SENP7ATMCASP3SENP8SENP6
SCHEMBL23911673 0.82 SMN1; SMN2 (0.53) SENP7ATMSMN1; SMN2NPC1RAB9A
SCHEMBL9505522 0.81 NPC1 (0.70) SENP7ATMSMN1; SMN2NPC1RAB9A
SCHEMBL10938852 0.78 NOTUM (0.56) SENP7ATMSMN1; SMN2NPC1RAB9A
SCHEMBL9987876 0.78 L3MBTL1 (0.50) SENP7ATMSMN1; SMN2NPC1RAB9A
SCHEMBL6041361 0.77 ATM (0.62) SENP7ATMRAB9ACASP3SENP8
SCHEMBL10906062 0.75 ATM (0.59) SENP7ATMSMN1; SMN2NPC1RAB9A
SCHEMBL30566762 0.75 ATM (0.59) SENP7ATMSMN1; SMN2NPC1RAB9A
SCHEMBL6041725 0.74 ATM (0.58) SENP7ATMSMN1; SMN2NPC1RAB9A
SCHEMBL6979612 0.74 KMT2A (0.56) SENP7ATMSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325336-B1 OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-08-04 EP disclosed
US-4929628-A Oxadiazole compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B. V. (NL) 1990-05-29 US disclosed
EP-0325336-A1 Oxadiazole compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-07-26 EP disclosed
EP-0036711-B1 PESTICIDAL HETEROCYCLIC COMPOUNDS, PROCESSES FOR PREPARING THEM, COMPOSITIONS CONTAINING THEM, AND THEIR USE FBC LIMITED (GB) 1985-12-04 EP disclosed
US-4414221-A MITICIDES, INSECTICIDES, APHIDICIDES FBC LIMITED (GB) 1983-11-08 US disclosed
EP-0036711-A2 Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use FBC LIMITED (GB) 1981-09-30 EP disclosed