⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408174 | 0.93 | ALDH1A1 (0.64) | — | |
| SCHEMBL29240398 | 0.93 | ALDH1A1 (0.64) | — | |
| SCHEMBL27438070 | 0.91 | ALDH1A1 (0.68) | — | |
| SCHEMBL29181658 | 0.87 | ALDH1A1 (0.58) | — | |
| SCHEMBL15791181 | 0.85 | — | — | |
| SCHEMBL28550275 | 0.84 | ALDH1A1 (0.59) | — | |
| SCHEMBL29181636 | 0.82 | ALDH1A1 (0.53) | — | |
| SCHEMBL28045839 | 0.79 | — | — | |
| SCHEMBL49856 | 0.79 | ALDH1A1 (0.62) | — | |
| SCHEMBL218953 | 0.79 | KDM4E (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024136777-A1 | δ-OXO HYDRAZIDE-HYDRAZONE DERIVATIVE COMPOUNDS WITH ANTI- CANCER ACTIVITY AND THE SYNTHESIS METHODS THEREOF | ISTANBUL UNIVERSITESI-CERRAHPASA REKTORLUGU (TR) | 2024-06-27 | — | — | WO | disclosed |
| EP-0434752-B1 | THERMOPHILIC ALGINATE LYASE FROM BACILLUS STEAROTHERMOPHILUS NRRL B-18394 | NOVO NORDISK A/S (DK) | 1993-08-04 | — | — | EP | disclosed |
| US-5139945-A | For degrading algal cell walls; used as a treatment agent in water cooling systems | NOVO INDUSTRI A/S (DK) | 1992-08-18 | — | — | US | disclosed |
| EP-0434752-A1 | THERMOPHILIC ALGINATE LYASE FROM BACILLUS STEAROTHERMOPHILUS NRRL B-18394. | NOVO NORDISK AS (DK) | 1991-07-03 | — | — | EP | disclosed |
| WO-1990002794-A1 | THERMOPHILIC ALGINATE LYASE FROM BACILLUS STEAROTHERMOPHILUS NRRL B-18394 | NOVO NORDISK A/S (DK) | 1990-03-22 | — | — | WO | disclosed |