Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 5/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509902 | 0.95 | KMT2A (0.61) | KMT2ARARBSRD5A2RXRARXRB | |
| SCHEMBL9319143 | 0.89 | KMT2A (0.69) | KMT2ARARBSRD5A2RXRARXRB | |
| SCHEMBL13928722 | 0.86 | KMT2A (0.57) | KMT2ARARBSRD5A2RXRARXRB | |
| SCHEMBL13861911 | 0.84 | MAPK1 (0.68) | RARBSRD5A2MAPK1HSD17B10PKM | |
| SCHEMBL9508656 | 0.83 | RARB (0.58) | KMT2ARARBMAPK1 | |
| SCHEMBL9507371 | 0.83 | RARB (0.58) | KMT2ARARBMAPK1 | |
| SCHEMBL9507432 | 0.83 | RARB (0.52) | KMT2ARARBSRD5A2RXRARXRB | |
| SCHEMBL9507377 | 0.83 | RARB (0.58) | KMT2ARARBMAPK1 | |
| SCHEMBL9477903 | 0.82 | RARB (0.61) | KMT2ARARBPDE4APDE4BPDE4C | |
| SCHEMBL11573867 | 0.81 | KMT2A (0.59) | KMT2ARARBSRD5A2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |