Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508054 | 0.95 | KMT2A (0.56) | KMT2AMAPK1CA1CA2RARB | |
| SCHEMBL9319143 | 0.93 | KMT2A (0.69) | KMT2AMAPK1CA1CA2RARB | |
| SCHEMBL11573867 | 0.85 | KMT2A (0.59) | KMT2AMAPK1CA1CA2RARB | |
| SCHEMBL7995208 | 0.85 | KMT2A (0.62) | KMT2AMAPK1CA1CA2RARB | |
| SCHEMBL10476865 | 0.85 | KMT2A (0.62) | KMT2AMAPK1CA1CA2RARB | |
| Hydrochloric Acid SCHEMBL10453860 | 0.83 | KMT2A (0.61) | KMT2AMAPK1CA1CA2RARB | |
| SCHEMBL8432243 | 0.82 | MAPK1 (0.73) | KMT2AMAPK1RARBPLA2G4BRXRA | |
| SCHEMBL8084708 | 0.82 | KMT2A (0.59) | KMT2AMAPK1RARBPLA2G4B | |
| SCHEMBL11570938 | 0.82 | RARB (0.60) | KMT2AMAPK1CA1CA2RARB | |
| SCHEMBL5400573 | 0.82 | MAPK1 (0.73) | KMT2AMAPK1RARBPLA2G4BRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388960-B1 | OPTICALLY ACTIVE COMPOUNDS AND THEIR PREPARATION AND USE | HITACHI, LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-5152919-A | Stability, chemical resistance, high speed response, large spo ntaneous polarization, molecular orientation and wide temperat ure range | HITACHI, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0388960-A1 | Optically active compounds and their preparation and use | HITACHI, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |