Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508072 | 1.00 | HCAR2 (0.44) | HCAR2MASP2F2ALDH1A1MAPT | |
| SCHEMBL11428593 | 0.91 | HCAR2 (0.47) | HCAR2MASP2F2ALDH1A1MAPT | |
| SCHEMBL11186784 | 0.87 | HCAR2 (0.48) | HCAR2MASP2F2ALDH1A1MAPT | |
| SCHEMBL774780 | 0.81 | ALDH1A1 (0.43) | HCAR2ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL774379 | 0.81 | ALDH1A1 (0.43) | HCAR2ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL23870571 | 0.81 | ALDH1A1 (0.43) | HCAR2ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL8165550 | 0.81 | ALDH1A1 (0.43) | HCAR2ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL19536211 | 0.81 | ALDH1A1 (0.43) | HCAR2ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL775555 | 0.81 | ALDH1A1 (0.43) | HCAR2ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL774781 | 0.81 | ALDH1A1 (0.43) | HCAR2ALDH1A1MAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322164-B1 | ETHANOLAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1993-09-22 | — | — | EP | disclosed |
| US-5039697-A | Adrenergic stimulants, bronchodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| US-5032609-A | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1991-07-16 | — | — | US | disclosed |
| US-5002966-A | Adrenergic Stimulants | GLAXO GROUP LIMITED (GB) | 1991-03-26 | — | — | US | disclosed |
| EP-0322164-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-06-28 | — | — | EP | disclosed |