SCHEMBL9508099

SCHEMBL9508099

Brc1cc2c(cc1Br)Sc1cc(Br)c(Br)cc1S2

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.37
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
APEX1 P27695 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507748 0.81 MAPK1 (0.40) AHR
SCHEMBL11593262 0.78 BCHE (0.33)
SCHEMBL356698 0.78 AHR (0.50) AHRCA1CA2CA4CA6
SCHEMBL9508084 0.76 AHR (0.60) AHR
SCHEMBL4707719 0.76 NOX1 (0.43)
SCHEMBL4708643 0.73 MAOA (0.43)
SCHEMBL9507682 0.73 GRIN2D (0.44)
SCHEMBL29561410 0.67 SNCA (0.40) AHR
SCHEMBL31121327 0.67 SNCA (0.40) AHR
SCHEMBL205436 0.67 SNCA (0.40) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0399293-B1 PROCESS FOR PREPARING 2-CHLORO-4-NITRO-ALKYLBENZENE BAYER AG (DE) 1993-09-01 EP disclosed
US-5095157-A Friedel-crafts catalyst BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0399293-A1 Process for preparing 2-chloro-4-nitro-alkylbenzene BAYER AG (DE) 1990-11-28 EP disclosed
US-3989715-A Process for manufacturing chlorothianthrenes HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-11-02 US disclosed