Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18139 | 0.77 | SHBG (0.53) | ESR1ESR2SLC6A2ALDH1A1CYP1A2 | |
| SCHEMBL10456186 | 0.76 | ESR1 (0.76) | ESR1ESR2TAAR1SLC6A2MEN1 | |
| SCHEMBL7806637 | 0.76 | ESR1 (0.76) | ESR1ESR2TAAR1SLC6A2MEN1 | |
| SCHEMBL572776 | 0.76 | ESR1 (0.76) | ESR1ESR2TAAR1SLC6A2MEN1 | |
| SCHEMBL18775 | 0.76 | TAAR1 (0.53) | ESR1ESR2TAAR1SLC6A2 | |
| SCHEMBL6157069 | 0.75 | SHBG (0.50) | ESR1ESR2SLC6A2ALDH1A1CYP1A2 | |
| SCHEMBL3480352 | 0.74 | SHBG (0.52) | ESR1ESR2SLC6A2ALDH1A1CYP1A2 | |
| SCHEMBL28445537 | 0.74 | TAAR1 (0.52) | ESR1ESR2TAAR1SLC6A2 | |
| SCHEMBL296781 | 0.73 | ESR1 (1.00) | ESR1ESR2TAAR1SLC6A2MEN1 | |
| SCHEMBL547164 | 0.73 | ESR1 (1.00) | ESR1ESR2TAAR1SLC6A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391191-B1 | (METH)ACRYLIC POLYMERS GRAFTED WITH POLYCARBONATE CHAINS, THEIR MANUFACTURE AND USE | BAYER AG (DE) | 1993-09-01 | — | — | EP | disclosed |