Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | HHAT | Q5VTY9 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2138396 | 0.90 | DRD1 (0.59) | DRD1ACEMTNR1BLIPEHHAT | |
| SCHEMBL9509161 | 0.82 | HHAT (0.61) | ACEHHATCYP2D6TRPM8 | |
| SCHEMBL21465733 | 0.80 | DRD1 (0.60) | DRD1ACEMTNR1BLIPEHHAT | |
| SCHEMBL10312392 | 0.80 | DRD1 (0.60) | DRD1ACEMTNR1BLIPERIPK1 | |
| SCHEMBL30878500 | 0.80 | DRD1 (0.60) | DRD1ACEMTNR1BLIPEHHAT | |
| SCHEMBL18711615 | 0.80 | DRD1 (0.60) | DRD1ACEMTNR1BLIPERIPK1 | |
| SCHEMBL9509146 | 0.80 | DRD1 (0.57) | DRD1ACEMTNR1BLIPETRPM8 | |
| SCHEMBL18701662 | 0.79 | DRD1 (0.56) | DRD1ACEMTNR1BLIPETRPM8 | |
| SCHEMBL18701598 | 0.79 | DRD1 (0.56) | DRD1ACEMTNR1BLIPETRPM8 | |
| SCHEMBL18701717 | 0.79 | DRD1 (0.56) | DRD1ACEMTNR1BLIPETRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | claimed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | claimed |
| EP-0230871-B1 | HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES | Monsanto Company (US) | 1993-09-22 | — | — | EP | disclosed |
| US-4755218-A | Reducing acetochlor injury to corn by applying with antidote | MONSANTO COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| EP-0230871-A2 | Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes | Monsanto Company (US) | 1987-08-05 | — | — | EP | disclosed |