SCHEMBL2138396

SCHEMBL2138396

CC1c2ccccc2CCN1C(=O)C(Cl)Cl

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.59
ACE P12821 2/20 0.48
MTNR1B P49286 1/20 0.47
LIPE Q05469 1/20 0.45
RIPK1 Q13546 1/20 0.43
AKR1C3 P42330 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42
GRM5 P41594 2/20 0.42
HHAT Q5VTY9 2/20 0.42
NPC1 O15118 1/20 0.42
SPR P35270 3/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508172 0.90 DRD1 (0.57) DRD1ACEMTNR1BLIPERIPK1
SCHEMBL9508177 0.83 ACE (0.49) DRD1ACEMTNR1BNPSR1HHAT
SCHEMBL9509170 0.82 KMT2A (0.45) DRD1NPC1
SCHEMBL10770517 0.82 ACE (0.48) DRD1ACEMTNR1BNPSR1HHAT
SCHEMBL9509872 0.82 MTNR1B (0.53) DRD1ACEMTNR1BNPSR1HHAT
SCHEMBL9511054 0.82 ACE (0.45) DRD1ACEMTNR1BNPSR1HHAT
SCHEMBL8045830 0.82 DRD1 (0.43) DRD1ACEMTNR1BLIPERIPK1
SCHEMBL21465733 0.81 DRD1 (0.60) DRD1ACEMTNR1BLIPERIPK1
SCHEMBL30878500 0.81 DRD1 (0.60) DRD1ACEMTNR1BLIPERIPK1
SCHEMBL18711615 0.81 DRD1 (0.60) DRD1ACEMTNR1BLIPERIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902118-B2 Herbicide and repellent adjuvant; reducing foliage retention; preventing damage to crops BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-03-08 US claimed
US-6936569-B2 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-08-30 US claimed
US-20050032645-A1 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-02-10 US claimed
EP-1258193-A1 Herbicidal compositions of tetrazolinone herbicides and antidotes therefor Syngenta Limited (GB) 2002-11-20 EP claimed
US-20020010096-A1 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2002-01-24 US claimed
US-6235682-B1 AQUEOUS SOLUTION CONTAINING REPELLENT ADJUVANT BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2001-05-22 US claimed
EP-0802732-B1 HERBICIDAL COMPOSITIONS OF 4-BENZOYLISOXAZOLE OR 2-CYANO-1,3-DIONE HERBICIDES AND ANTIDOTES THEREFOR ZENECA LTD (GB) 2000-04-19 EP claimed
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP claimed
US-5627131-A Herbicidal compositions of 4-benzoylisoxazole and antidotes therefor ZENECA LIMITED (GB) 1997-05-06 US claimed
EP-0252897-B1 Formulations of water-dispersible granules and process for preparation thereof MONSANTO CO (US) 1994-02-16 EP claimed
EP-0230871-B1 HALOACYL 1-SUBSTITUTED-1,2,3,4-TETRAHYDROISOQUINOLINES AS HERBICIDE ANTIDOTES Monsanto Company (US) 1993-09-22 EP claimed
US-4755218-A Reducing acetochlor injury to corn by applying with antidote MONSANTO COMPANY (US) 1988-07-05 US claimed
EP-0252897-A2 Formulations of water-dispersible granules and process for preparation thereof Monsanto Company (US) 1988-01-13 EP claimed
EP-0236268-A1 Plant protection by means of N-halogenoacetyl isoquinolines against herbicidal halogen acetanilides CIBA-GEIGY AG (CH) 1987-09-09 EP claimed
EP-0230871-A2 Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes Monsanto Company (US) 1987-08-05 EP claimed
US-7902118-B2 Herbicide and repellent adjuvant; reducing foliage retention; preventing damage to crops BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-03-08 US disclosed
US-6936569-B2 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-08-30 US disclosed
US-4755218-A Reducing acetochlor injury to corn by applying with antidote MONSANTO COMPANY (US) 1988-07-05 US disclosed
EP-0236268-A1 Plant protection by means of N-halogenoacetyl isoquinolines against herbicidal halogen acetanilides CIBA-GEIGY AG (CH) 1987-09-09 EP disclosed
EP-0230871-A2 Haloacyl 1-substituted-1,2,3,4-tetrahydroisoquinolines as herbicide antidotes Monsanto Company (US) 1987-08-05 EP disclosed