Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 4/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.34 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066613 | 0.75 | TBXA2R (0.65) | TBXA2R | |
| SCHEMBL5412370 | 0.75 | HRH1 (0.56) | TRPA1SIGMAR1HTR2AHRH1 | |
| SCHEMBL9507218 | 0.75 | TBXA2R (0.76) | TBXA2RHTR2AHRH1 | |
| SCHEMBL5410942 | 0.73 | HRH1 (0.58) | TRPA1SIGMAR1HTR2AHRH1 | |
| SCHEMBL9308823 | 0.72 | TBXA2R (0.39) | TBXA2RTRPA1SIGMAR1HTR2AHRH1 | |
| SCHEMBL9310154 | 0.72 | TBXA2R (0.39) | TBXA2RTRPA1SIGMAR1HTR2AHRH1 | |
| SCHEMBL9308785 | 0.72 | TBXA2R (0.39) | TBXA2RTRPA1SIGMAR1HTR2AHRH1 | |
| SCHEMBL9307887 | 0.72 | TBXA2R (0.39) | TBXA2RTRPA1SIGMAR1HTR2AHRH1 | |
| SCHEMBL9309778 | 0.70 | TBXA2R (0.38) | TBXA2RTRPA1SIGMAR1HTR2AHRH1 | |
| SCHEMBL3605125 | 0.70 | HPGD (0.38) | TBXA2RTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |