Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508882 | 0.91 | SLC2A1 (0.46) | SLC2A1 | |
| Bromide SCHEMBL9510883 | 0.89 | SLC2A1 (0.46) | SLC2A1 | |
| Hydrochloric Acid SCHEMBL9776658 | 0.82 | SLC2A1 (0.56) | SLC2A1NPC1LMNAPKMNFKB1 | |
| SCHEMBL9508885 | 0.81 | SLC2A1 (0.57) | SLC2A1 | |
| Hydrochloric Acid SCHEMBL9776703 | 0.80 | SLC2A1 (0.56) | SLC2A1 | |
| SCHEMBL9508917 | 0.79 | SLC2A1 (0.47) | SLC2A1 | |
| SCHEMBL9508265 | 0.79 | — | — | |
| SCHEMBL9776700 | 0.78 | SLC2A1 (0.83) | SLC2A1NPC1LMNAPKMNFKB1 | |
| SCHEMBL9776757 | 0.77 | SLC2A1 (0.48) | SLC2A1 | |
| Hydrochloric Acid SCHEMBL9776677 | 0.77 | SLC2A1 (0.86) | SLC2A1NPC1LMNAPKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404322-B1 | QUINAZOLINE DERIVATIVES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-22 | — | — | EP | claimed |
| US-5064833-A | Substituted quinazoline derivatives for use in gastrointestinal diseases | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1991-11-12 | — | — | US | claimed |
| EP-0404322-A1 | Quinazoline derivatives | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1990-12-27 | — | — | EP | claimed |
| JP-3017068-A | — | — | None | — | — | JP | disclosed |
| EP-0404322-B1 | QUINAZOLINE DERIVATIVES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-09-22 | — | — | EP | disclosed |
| US-5064833-A | Substituted quinazoline derivatives for use in gastrointestinal diseases | SMITHKLINE BEECHAM INTERCREDIT B.V. (GB) | 1991-11-12 | — | — | US | disclosed |
| JP-H0317068-A | SUBSTITUTED QUAINAZOLINE DERIVATIVE | SMITHKLINE BEECHAM INTERCREDIT BV | 1991-01-25 | — | — | JP | disclosed |
| EP-0404322-A1 | Quinazoline derivatives | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1990-12-27 | — | — | EP | disclosed |