Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506160 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9507613 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9506166 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9506292 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9506138 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9507596 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9506149 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9506321 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9510040 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES | |
| SCHEMBL9508463 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2D6RARBCYP3A4PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295370-B1 | LIQUID-CRYSTALLINE 5-PHENYL PYRIMIDINE DERIVATIVES WITH AN SC OR SC (ASTERISK) PHASE, AND METHOD FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | claimed |
| US-4906752-A | Liquid-crystal 5-phenylpyrimidine derivatives having sc or sc* phases and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | claimed |
| EP-0295370-A1 | Liquid-crystalline 5-phenyl pyrimidine derivatives with an Sc or Sc (asterisk) phase, and method for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-12-21 | — | — | EP | claimed |
| EP-0295370-B1 | LIQUID-CRYSTALLINE 5-PHENYL PYRIMIDINE DERIVATIVES WITH AN SC OR SC (ASTERISK) PHASE, AND METHOD FOR PREPARING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-11 | — | — | EP | disclosed |
| US-4906752-A | Liquid-crystal 5-phenylpyrimidine derivatives having sc or sc* phases and a process for preparing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-06 | — | — | US | disclosed |